Sammanställning av godkända forskningsprojekt
Ansvarig forskare | Lärosäte | Projektnamn | Publikationer |
Helena Carén | GU | Improved diagnostics of pediatric CNS tumors based on DNA methylation classification | |
Monica Nistér/Joakim Lundeberg | KTH/KI | Analysis of spatial gene expression in childhood brain tumors | Spatially resolved clonal copy number alterations in benign and malignant tissue |
John Inge Johnsen/Ninib Baryawno | KI/K | Single cell RNA-seq of childhood brain tumorus | Genomic tumor evolution dictates human medulloblastoma progression |
Fredrik Swartling | UU | Developing xenografts and cell lines from CNS tumors in children for molecular studies and novel treatment models | |
Emma Tham/Magnus Nordenskjöld | KI/K | Analys av cell-fritt tumör-DNA i blod och cerebrospinalvätska | Simultaneous Ultra-Sensitive Detection of Structural and Single Nucleotide Variants Using Multiplex Droplet Digital PCR in Liquid Biopsies from Children with Medulloblastoma |
Anna Pasetto | KI | Nya immunterapier för barnhjärncancer (hjärnstam/ ponsgliom) | |
Anna Dahlin | UmU | Genotyp-fenotyp studier i barnhjärntumörer | |
Lisa Westerberg | KI | Studier av pediatriskt lymfom | |
Klas Blomgren | KI/K | Studier av tumörceller och immunceller vid hjärntumörer hos barn | |
Peter Lundberg | RÖ/LiU | Förbättrad diagnostik av tumörer i centrala nervsystemet hos barn och ungdomar genom applicering digital patologi | Pediatric brain tumor classification using digital histopathology and deep learning: evaluation of SOTA methods on a multi-center Swedish cohort |
Petter Brodin/Per Kogner | KI | ISAC: immune monitoring of pediatric cancer patients | Systems-level immunomonitoring in children with solid tumors to enable precision medicine |
Gustaf Ljungman | UU/LiU | Pharmacogenomics in pediatric oncology patients with focus on chemotherpay-induced toxicity including myelosuppression | |
Martin Dalin | GU | Personalized analysis of circulating tumor DNA: A guide for treatment decisions in childhood cancer | |
Helena Carén | GU | Integrated analyses of paediatric brain tumours focusing on epigenetic aberrations | |
Lena-Maria Carlsson | K | LOGGIC Core – En internationell molekylär databas för låggradiga gliom hos | |
Svetlana Lagercrantz | K | Molekylär karakterisering och kliniska aspekter på familjära cancersyndrom orsakade av TP53 mutationer i den svenska befolkningen. | |
Anna Dahlin | UmU | Genotype-Phenotype Investigations in Childhood Brain Tumors – Phase II | |
Felix Haglund | K/KI | Proteogenomic and functional characterization of sarcomas in a prospective clinical setting | |
Susanne Schlisio | KI | Utforska Neuroblastom – cellstadiedynamik och plasticitet vid tumörbildning och terapiresistens | |
Fredrik Bäcklund | RU/K | Genetiska förändringar i lymfom hos barn | |
Sten Linnarsson | KI | Cell identity in adult and pediatric brain tumors | |
Erik Sundström | KI | Pediatric ependymoma – defining cell state transitions as basis for future treatments | |
Emma Tham | KI | The use of cerebrospinal fluid for diagnosis, prognosis and monitoring of treatment response in patients with childhood brain tumors |